Quantification of 5-Methylcytosine in DNA by the Chloroacetaldehyde Reaction
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چکیده
منابع مشابه
Quantification of 5-methylcytosine in DNA by the chloroacetaldehyde reaction.
The study of changes in genome-wide levels of DNA methylation has become a key focus for understanding the epigenetic regulation of gene expression. Many procedures exist to study DNA methylation, falling into two categories: gene-specific and genome-wide. Genome-wide methylation analysis is best performed by DNA hydrolysis followed by HPLC; however, it requires access to an HPLC machine, which...
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Direct Sensing of 5-Methylcytosine by Polymerase Chain Reaction**
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ژورنال
عنوان ژورنال: BioTechniques
سال: 1999
ISSN: 0736-6205,1940-9818
DOI: 10.2144/99274st05